Chinese scientists have discovered that a substance produced in the liver may have similar effects on lifespan extension as calorie restriction.
In a study published in the journal Nature, researchers examined the effects of lithocholic acid (LCA) on genetically modified mice with human tissues. The results were then compared to the effects of calorie restriction.
The researchers found that LCA, which is typically produced in the liver, can accelerate muscle regeneration, and increase grip strength and running ability.
Earlier research had shown that during calorie restriction, mammals accumulate LCA, which activates a crucial molecule in metabolism called AMP-activated protein kinase (AMPK).
AMPK plays a vital role in the aging process, as it helps control inflammation and nerve degeneration by becoming active when glucose levels are low.
